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Psychedelics | Ancient Wisdom

Before the Microscope: The Sacred History of Psilocybin Mushrooms

A snapshot into the origin story of mushroom as entheogen

5 min readApr 19, 2025

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a microscope in an ancient rain forest looking at psilocybin mushrooms, psychedelics, entheogens

Long before molecular diagrams or clinical trials, before psilocybin was a word spoken by psychiatrists and psychonauts, there were mushrooms.

And.

There were people who revered them.

Before Science, There Was Spirit

Today, psilocybin mushrooms — especially Psilocybe cubensis — are at the center of many conversations about mental health, consciousness, and personal transformation.

But their mycelial roots run far deeper than contemporary research. For thousands of years, they weren’t called “psychedelics” or “substances.” They were sacraments — entheogenic organisms consumed in ceremony and sacred ritual.

Across Mesoamerica and beyond (psilocybin-containing fungi are indigenous to every continent except Antarctica), these mushrooms were embedded in myth, ritual, healing, and cosmology.

To understand their role in our modern world, we must first look back — far back — before scientific analysis, before prohibition, before the microscope. Back when mushrooms were spirit…

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Lisa Loewen, MAIS, RCC
Lisa Loewen, MAIS, RCC

Written by Lisa Loewen, MAIS, RCC

Registered Clinical Counsellor | Artist | Poet | Co-Founder Humanity Academy | Free Courses www.humanityacademy.life

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